Clinical evaluation of HIFU combined with GnRH-a and LNG-IUS for adenomyosis patients who failed to respond to drug therapies: two-year follow-up results
نویسندگان
چکیده
Objective To investigate the clinical effect of high intensity focused ultrasound (HIFU) ablation combined with gonadotropin-releasing hormone agonist (GnRH-a) and levonorgestrel-releasing intrauterine system (LNG-IUS) in treatment adenomyosis patients who failed to respond drug therapies.Study design A total 47 had therapies no fertility desires were treated HIFU GnRH-a LNG-IUS. The score dysmenorrhea menstrual volume measured at pre 6-, 12-, 18-, 24-month post-HIFU.Results All completed without major postoperative complications. Compared symptom scores before treatment, decreased significantly 6, 12, 18 24 months after (p < 0.05), but significant difference was observed between > 0.05). success rate 100%, 95.7% 93.6% respectively treatment.Conclusion therapeutic regimen HIFU, LNS-IUS is safe effective, which can be an alternative option for avoid adenomyomectomy or hysterectomy.
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ژورنال
عنوان ژورنال: International Journal of Hyperthermia
سال: 2021
ISSN: ['1464-5157', '0265-6736']
DOI: https://doi.org/10.1080/02656736.2021.1967467